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This 10X buffer concentrate is optimized for creating a pH gradient for monoclonal antibody (mAb) charge variant separations. It is designed for use with BioResolve SCX columns.
10X buffer concentrate
Optimized for creating a pH 5.0 to pH 10.2 gradient
Designed for use in monoclonal antibody (mAb) charge variant separations
Developed alongside BioResolve SCX columns
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
This 10X buffer concentrate B is specifically optimized for use in creating a pH 5.0 to pH 10.2 gradient, essential for monoclonal antibody (mAb) charge variant separations. It is designed to be used alongside BioResolve SCX columns and features a pH of 10.2.
Optimized for creating a pH 5.0 to pH 10.2 gradient.
Aids in monoclonal antibody (mAb) charge variant separations.
Designed for use with BioResolve SCX columns.
Features a pH of 10.2.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
PKC-theta inhibitor 1 is an orally active, selective ATP-competitive inhibitor of protein kinase C theta (PKCθ) intended for preclinical research. It exhibits high binding potency (Ki = 6 nM), suppresses T-cell-mediated release of proinflammatory cytokines in cellular assays (IL-2 IC50 = 0.21 μM; IL-17 IC50 = 1 μM), and has molecular formula C17H15F3N4O with a molecular weight of 348.32 g·mol⁻¹. For research use only.
Selective ATP-competitive inhibition of PKCθ with high binding potency.
Demonstrated cellular activity against IL-2 and IL-17 production.
Orally active compound with in vivo efficacy in autoimmune models.
High chemical purity suitable for research applications.
Available in small pack sizes for dose-ranging and pilot studies.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More